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It helps to get a realistic perspective on what GLP-1s actually do long-term

Aphexda is the first approved therapeutic for BioLineRx, which also has offices in Waltham, Mass

Over time, the dosage is typically increased to optimize your weight loss results

The goal isn't to stay on medication indefinitelyit's to exit strategically so behavioral changes become the anchor holding your results

CV standard-of-care treatments at baseline included 1,2 : Medication Class Lipid-lowering therapy Platelet aggregation inhibitors Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers Beta-blockers Percentage of Patients (N=17,604) 90% 86% 74% 70% Throughout the trial, CV therapies could be adjusted at investigator discretion according to current standard of care 1 Baseline cardiometabolic parameters 1 Heart rate A1c Systolic blood pressure Diastolic blood pressure Triglycerides Total cholesterol LDL cholesterol HDL cholesterol Wegovy injection (n=8,803) 69 bpm 5.8% 131 mm Hg 79 mm Hg 138.6 mg/dL 155.5 mg/dL 78.5 mg/dL 44.1 mg/dL Placebo (n=8,801) 69 bpm 5.8% 131 mm Hg 79 mm Hg 139.5 mg/dL 156 mg/dL 78.5 mg/dL 44.2 mg/dL *Standard of care included CV risk-factor management and individualized healthy lifestyle counseling (including diet and physical activity)