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After pre-incubation, cells were incubated in KRB buffer containing 2- or 16.8-mM glucose (Sigma-Aldrich) at 37 C for 30 min, respectively

For data not conforming to a normal distribution, comparisons between two groups were conducted using the MannWhitney U test, and comparisons among multiple groups were performed using the KruskalWallis ( H ) test

B12 given intravenously provide a concentrated dose of B12 directly to the bloodstream or muscle via injection

After transplantation for 7 days, these mice were treated with JMF4073 for 14 days

However, these findings cannot be extrapolated to transdermal delivery without specific evidence demonstrating equivalent bioavailability and pharmacokinetics