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The SOUL trial (2025), a large-scale, double-blind, placebo-controlled study, evaluated once-daily oral semaglutide in 9,650 patients with T2DM and established atherosclerotic cardiovascular disease, chronic kidney disease, or both

Considering the established involvement of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway and transforming growth factor-beta1 (TGF-1) in RA, this research aimed to assess efficacy and safety of L-carnitine as an adjunct therapy targeting these pathways

That opening drove explosive growth

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The analysis showed no significant protection against the wet form of AMD