Alongside nausea, vomiting and constipation, clinicians are now seeing a marked increase in haemorrhoids (piles) among patients using GLP-1 medications a condition that can be painful, distressing and, in some cases, mistaken for more serious disease
Contradictory findings from these studies could be likely explained, at least partly, by small sample sizes (and, consequently, by limited statistical power to detect associations) and also by narrow age ranges investigated (Der et al., 2012)
and other factors described in the Risk Factors and other sections of our most recently filed Quarterly Report on Form 10-Q, our most recently filed Annual Report on Form 10-K, and other current and periodic reports we file from time to time with the Securities and Exchange Commission
The future of GLP-1RA therapy is promising
The enzyme concentration is expressed in international units per gram of protein [18]