125,207,208 Drugs targeting both GLP-1 and glucagon receptors are currently under development, and it is vital to examine their indirect effects on CYP gene expression
All experimental techniques followed the guidelines for the Care and Use of Laboratory Animals and were conducted in compliance with the ARRIVE guidelines
CrossRef Leptin Promotes White Adipocyte Browning by Inhibiting the Hh Signaling Pathway Jie Wang, Jing Ge, Haigang Cao, Xiaoyu Zhang, Yuan Guo, Xiao Li, Bo Xia, Gongshe Yang, Xine Shi Cells.2019
Pregnancy and breastfeeding GLP-1 medications should be discontinued before pregnancy
The most common side effects are gastrointestinal, including nausea (15-20% of patients), diarrhea (9-10%), vomiting (8-9%), and abdominal pain (6-8%)