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Modulations of gene expression related to inflammatory signaling, angiogenic regulators, cell cycle control, and structural matrix proteins have been documented in preclinical and in vitro systems
Side effects are rare and typically mild, such as slight discomfort at the injection site or temporary bruising
Neurological symptoms may start improving within 12 weeks, but longstanding complications can require 36 months of treatment, with some damage potentially irreversible
PMID 14523363
Effects of oral -lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double-blind, placebo-controlled trial
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