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SURMOUNT-OSA, completed in 2024, led to FDA approval of Zepbound for moderate-to-severe obstructive sleep apnea in adults with obesity in December 2024

However, in ME/CFS and dysautonomia, this vital switching mechanism becomes severely impaired, leaving patients unable to generate the rapid ATP required for basic daily activities

While highly effective, it presents a distinct side effect profile including gastrointestinal issues and dysesthesia, leading to a slightly higher discontinuation rate in studies

Telemedicine Providers: Licensed healthcare providers offering consultations and prescriptions via telehealth platforms, depending on local laws and regulations