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When Anxiety Means You Should Contact Your Provider Persistent chest pressure Panic episodes Heart rate consistently elevated beyond 20 bpm above baseline Inability to eat adequately Thoughts of discontinuing the medication due to discomfort A dose reduction or slower titration schedule can often resolve the issue

Furthermore, the direction of confounding is uncertain, as healthier and more adherent patients may be selectively prescribed GLP-1 RAs (confounding by indication)

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