And even more striking, 92.8% of that weight loss came from fat
Heterozygous deletion of GLUT3 correlates directly with expression levels of GLUT3 and influences glycolysis rates in the human immune system ( + T cells and FLS, which resulted in increased proliferation and expression of glucose transporters GLUT1 and GLUT3 in FLS (48)
However, as gallbladder disease is not an issue with sodium-glucose co-transporter-2 (SGLT-2) inhibitors (with similar weight loss) (89), and gallbladder events also occurred in GLP-1RA-treated patients well after weight reduction (90), other mechanisms are possibly in play
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