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183 Although no rigorous randomized controlled trials have shown estriol to be safer or more effective than estradiol, 184 some physicians experienced in prescribing compounded hormones prefer transdermal formulations comprising primarily estriol (eg, Bi-Est)

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However, the limited follow-up duration of 6 months raised concerns about potential reverse causality, as undetected suicidal ideation and medical conditions might have influenced the choice of particular anti-obesity or anti-diabetic drugs

Add breastfeeding challenges into the mix and many mothers feel a lot of pressure to do everything right, which can take an emotional toll