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TB-500 is a synthetic fragment of Thymosin Beta-4, a 43-amino acid protein involved in actin regulation and cytoskeletal organisation, with a molecular formula of CHNOS and molecular weight of approximately 4,963 g/mol
In cancer cells, mutations in succinate dehydrogenase subunit B (SDHB) cause susceptibility to familial pheochromocytoma 99 and familial paraganglioma 100 as well as gastrointestinal stromal tumors 101
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