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GIP receptor activation enhances insulin secretion in a glucose-dependent manner and, based on preclinical and early clinical data, may improve insulin sensitivity in adipose tissue

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After the third immunization, all mice in the 1-g and 4-g sVLP groups developed neutralizing antibodies with geometric mean titers of 169 and 239, respectively, at week 6 (Fig

12 Another valid concern related to the long-term use of GLP-1RAs is the potential loss of skeletal muscle mass, which may worsen existing sarcopenia, cachexia, or frailty among older individuals or those with specific chronic conditions

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