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In obesity, NNMT activity is unusually high in fat cells, which means a lot of nicotinamide gets thrown out before it can be turned into NAD+
When it runs low, the whole operation starts to grind to a halt
Studied for effects on glucose tolerance and insulin response in preclinical models of metabolic syndrome
Helps with the metabolism of fats and carbohydrates
Instead of suppressing your appetite or forcing you to eat less, it targets the cellular machinery that tells your fat cells to store or release energy
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