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It may lose its natural glow, develop wrinkles, sag, and show signs of pigmentation
Front Cell Dev Biol 13:1521336 Selvaraj NR, Nandan D, Nair BG, Nair VA, Venugopal P, Aradhya R (2025) Oxidative stress and redox imbalance: common mechanisms in cancer stem cells and neurodegenerative diseases
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Protein S -glutathionylation is an important post-translation modification, providing protection of protein cysteines from irreversible oxidation and, at the same time, serving to transduce a redox signal by changing structure/function of the target protein
Therefore, the observed effects of lactate shuttling on brain activation and behavior likely involve the integrated contribution of both its energy-delivering and its signal-transducing functions
