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Its more common than people think especially if you eat little or no meat, deal with gut issues, or have been under constant stress

This includes: Diluting the Vitamin B12 in a compatible IV solution Administering the infusion over a specified period, typically 30 minutes to an hour Monitoring the patient for any adverse reactions during and after the infusion By carefully considering these factors and following established guidelines, healthcare providers can optimize IV Vitamin B12 therapy for their patients

Patients with pre-existing peripheral neuropathy might report changes in sensation during treatment

If reticulocytes have not increased after treatment or if reticulocyte counts do not continue at least twice normal as long as the hematocrit is less than 35%, diagnosis or treatment should be reevaluated

18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms