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Some people report mild digestive discomfort, particularly when starting at higher doses
However, some people may experience mild ketosis due to reduced calorie intake during weight loss
MALA is extremely rare and occurs only in patients with severe kidney disease, acute illness, or dehydrationnot as a direct result of adding semaglutide to metformin therapy
In the context of diabetes research, Tirzepatide is utilized in models like the Zucker diabetic fatty (ZDF) rat or streptozotocin-induced diabetic models to investigate its impact on glycemic control
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