While providing local GI benefits, BPC-157 demonstrates systemic bioavailability after oral administration, distributing throughout the body to support healing in joints, tendons, muscles, and other tissues
Interestingly, the same gene expression research that identified this theoretical risk also found that GHK-Cu suppresses RNA production in 70% of 54 genes overexpressed in metastatic colon cancer
[1] For this reason, it might be advised to remain in the clinic for 10-15 minutes after the first injection to ensure you dont react
In a phase II trial, adults with a BMI of 30 or 27 kg/m with comorbidities were randomized to receive efpeglenatide at doses of 4 mg weekly, 6 mg weekly, 6 mg biweekly, or 8 mg biweekly, or a placebo, all combined with a hypocaloric diet [17]
Since its discovery, the compound has been studied extensively in laboratory settings examining peptide communication pathways and molecular regulatory processes