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The idiopathic pulmonary fibrosis indication has attracted particular clinical attention given strong preclinical data in murine models and the encouraging signals from the Mayo Clinic's human trial of dasatinib and quercetin, which showed measurable improvements in six-minute walk distance and pulmonary function at 20-week follow-up

Brevetti, G., Attisano, T., Perna, S., Rossini, A., Policicchio, A., and Corsi, M

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In streptozotocin (STZ)-treated mice and HG-exposed TECs, IGF2BP3 suppresses mitochondrial fission to inhibit TECs apoptosis by activating CAMK1 (71)