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Cobalamin separates from the protein during digestion, and a substance called intrinsic factor binds to cobalamin for the body to absorb it into the blood

Intermittent claudication in peripheral arterial disease In peripheral arterial disease, atherosclerosis of the arteries that supply the lower extremities may diminish blood flow to the point that the metabolic needs of exercising muscles are not sufficiently met, thereby leading to ischemic leg or hip pain known as claudication (see the page on Intermittent Claudication in Peripheral Arterial Disease) (63)

Both peptides are composed of specific sequences of amino acids that influence cellular signaling pathways

However, as with any medical therapy, there may be situations where discontinuing the medication becomes necessary or desirable

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