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Melanin is the pigment that determines skin color, which is largely influenced by sun exposure

Seek urgent medical help if you experience severe persistent abdominal pain (with or without vomiting), signs of dehydration, or inability to keep fluids down, as these could indicate serious side effects

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Patients should monitor their blood glucose levels closely upon initiating treatment and seek immediate medical help if they notice any severe side effects like persistent stomach/abdominal pain or unusual tiredness

Other medications for high blood pressure, which can increase the effects of beta-blockers Some antidepressants Some drugs for diabetes (including insulin and pills) Medications for asthma, chronic bronchitis, emphysema, or chronic obstructive pulmonary disease (COPD) Allergy shots Antacids that contain aluminum Over-the-counter (OTC) cough, cold, or allergy medicines Beta-Blockers, Alcohol, and Caffeine Beta-Blockers and Pregnancy Tell your doctor if you're pregnant or might become pregnant while taking a beta-blocker