Impaired GLP-1 secretion is considered a significant component of the pathology of overweight and obesity, metabolic syndrome and type 2 diabetes, as individuals with these conditions often exhibit reduced GLP-1 release in response to food intake compared to healthy individuals
Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV: C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism
Well, I suppose the only thing this proves is how useless I am, Sinclair told me, frowning
Cells were seeded in 96-well plates at 2 10 5 cells/well unless otherwise indicated
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