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Collagenase Clostridium Histolyticum
True, R
Initially developed as glucose-lowering therapies, both classes have shown impressive cardiovascular and kidney-protective effects [17,18]
Cell 156(12):8496
15 A significant nuance of this system is the NCE-1 provision, which allows a generic manufacturer to file an ANDA with a Paragraph IV certification four years after the NCEs approval, provided they challenge at least one of the patents listed in the FDAs Orange Book
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