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The time to exhaustion was recorded as the duration from the start of the swimming test until the mouse was fully submerged for 8 consecutive seconds without resurfacing [10]

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A 2023 analysis of the existing literature recommended not drinking coffee sooner than 8 hours before bedtime

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Both L-carnitine loss into the dialysate and impaired synthesis by the kidneys contribute to a progressive carnitine deficiency in patients with end-stage renal disease (ESRD) undergoing hemodialysis (71)