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Research published in major diabetes journals demonstrates that adding a GLP-1 agonist to metformin monotherapy produces additional reductions in hemoglobin A1c (HbA1c) of 12 percent, along with weight loss averaging 510 pounds beyond what metformin achieves alone

Metformin also comes with gastrointestinal side effects that make compliance difficult, and it does not directly address the appetite dysregulation that accompanies insulin resistance

A typical Mounjaro prescription without insurance costs about $1,474 for four, 5 mg single-use pens (a one-month supply), but by using your SingleCare discount, you can pay as low as $875 for your prescription, saving about $600 per month

Some doctors estimate that as many as 10% of patients stopped using semaglutide medications like Ozempic due to these risks

Then the company posts results of the testing on their website for reference