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2.3 Alteration of the gut microbiota With the emergence of advanced sequencing technologies, it has become apparent that metformin mitigates the imbalance in gut microbiota associated with T2DM and its subsequent impact on host metabolism

Arch Neurol 67:849854 Echaniz-Laguna A, Zoll J, Ponsot E et al (2006) Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: a temporal study in man