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doi:10.1007/s12011-019-01954-6

Furthermore, we did not use operationalized criteria (for example, Diagnostic and Statistical Manual 5th edition) to define the populations of interest because these would not be applicable across animal and human studies, but instead relied on the definitions provided by the individual articles

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5-Amino-1MQ selectively blocks NNMT, preventing methyl-group transfer and, in research models, helping preserve SAM and NAD availability

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