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Given its role in catalyzing the conversion of pyruvate to lactate in glycolytic cancer cells and the observation that LDHA deficiency results in only relatively mild symptoms, such as exertional myopathy, LDHA represents a pivotal and safe therapeutic target (150,167)
Glucagon-like peptide-1 is a hormone made in the gut that helps regulate blood sugar levels
"The regulatory landscape has shifted, and pharmacies that continue to produce products that are essentially copies of commercially available drugs may face FDA enforcement," says Braverman
Where are the knowledge gaps, and what still needs investigation
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The studies showing significant GLP-1 modulation come primarily from animal models and cell culture experiments
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