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The acylation allows it to bind albumin, extending its plasma half-life to approximately 13 hours compared to native GLP-1's half-life of roughly 2 minutes [2]
It is primarily caused by telogen effluvium triggered by rapid weight loss and caloric restriction, rather than the medication itself
The firm dubbed the discontinuation rates overall acceptable, with rates lower in patients with a higher BMI
The American Diabetes Association Standards of Care recommends regular assessment of glycemic control, weight trends, and medication tolerance in patients receiving GLP-1 receptor agonists
H., Winayanuwattikun, W., Kim, S
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