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Q: Does Dihexa work the same way as conventional nootropics or stimulants

For serum samples, 75 L of chloroform:methanol extraction solvent (v:v = 1:2) was added to 20 L of mouse serum, with the exception of the serum from WT, Gclc L-KO, Nrf2 L-KO, and L-DKO mouse serum, for which 20 L of mouse serum was combined with 180 L of chloroform:methanol extraction solvent (v:v = 1:2) containing internal standards at the final concentrations: 5 nM D7-Sphinganine (Avanti Polar Lipids Inc., Cat# 860658), 12.5 nM D3-Deoxysphinganine (Avanti Polar Lipids Inc., Cat# 860474), and SPLASH LIPIDOMIX (1:1000, Avanti Polar Lipids Inc., Cat# 330707)

This preserves nicotinamide for NAD production, improving energy and fat-burning efficiency

Alpha-methylaminoisobutyric acid (MeAIB) was treated 1 to 4 hours before the electrophysiological recording

This reaction breaks the disulfide bonds, converting them into two thiol groups, and facilitates targeted drug release where it is needed most