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When to seek medical advice: Severe or persistent vomiting preventing medication or fluid intake Signs of allergic reaction (rash, facial swelling, difficulty breathing) Severe diarrhoea lasting more than 48 hours Diarrhoea containing blood or mucus, or accompanied by severe abdominal cramping Worsening infection symptoms despite antibiotic treatment Severe or acute abdominal pain (which could indicate pancreatitis or gallbladder disease) If you cannot keep fluids or medicines down or are severely dehydrated, seek medical advice promptly

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Diabetes and neurodegenerative diseases A growing body of evidence supports the link between diabetes and an increased risk of neurodegenerative diseases such as AD and PD