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Key Na transporters and channels found in astrocytes include the Na + /K + pump, ionotropic receptors such as AMPA and NMDA receptors, TRP1/4/5 channels and GABA and glycine transporters

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However, there is also considerable data for other solid cancers, suggesting a potential role in reducing cell proliferation and invasiveness, modulating gene expression, repairing DNA damage, and possibly sensitizing to systemic therapies (3745)

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GHK-Cu is frequently positioned as a later-phase or adjunctive agent rather than a first-line intervention