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These effects create synergistic benefits that exceed what would be expected from simple addition of single-pathway therapies
Conversely, although off-label use of GLP-1 RA for overweight and obesity cannot be excluded, such use was likely limited in the present study given existing prescription guidelines and regulatory vigilance
Current prescribing remains guided by licensed indications for diabetes and weight management
The more controversy they can stir up around GLP-1 meds, the better for their bottom line
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