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Key points about elevated B12: Water-soluble vitamin with significant hepatic storage capacity Elevated levels defined as exceeding laboratory upper reference limit Often discovered incidentally during routine blood tests May reflect underlying pathology rather than toxicity Persistent elevation should be confirmed with repeat testing It is important to note that high B12 levels are generally not considered toxic in the same way as fat-soluble vitamins
The middle third of the anterior and lateral thigh provides the safest zone with the most consistent subcutaneous tissue depth
According to Professor Adrian R Martineau, 1 March 2015, in his article discussing the main recommendations for healthcare practitioners in NICE Public Health (PH) guidance 56 on Vitamin D: increasing supplement use among at-risk groups: "Health professionals do not need to routinely test vitamin D status in asymptomatic people in at-risk groups before advising them to take a vitamin D supplement
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