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For this reason, a phase 3 trial shows that retatrutide patients are losing up to 30 percent of their body weight (other GLP-1 drugs hover somewhere around 15 to 20 percent )

They operate at fundamentally different points in the endocrine cascade, and conflating them leads to failed research protocols

In the weight management trials using semaglutide 2.4 mg, approximately 44% of participants experienced nausea at some point during treatment compared to 16% receiving placebo