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62,100 Additionally, mitochondrial iron uptake, MPTP opening, and liver injury were significantly reduced in MCFU gene knockout mice exposed to APAP, 101 and selective chelation of iron in lysosomes with starch-desferal and the general iron chelator DFO also effectively prevented APAP-induced liver injury

Ileus or bowel obstruction Gallbladder disease and gallstones Pancreatitis and pancreatic injury Dehydration , electrolyte imbalances , and kidney strain Weight loss outside expected ranges or malnutrition in some cases, including individuals using these drugs, such as Ozempic, for weight loss Vision loss and rare visual conditions such as NAION , with some plaintiffs reporting symptoms consistent with naion even before clear diagnosis Concerns over thyroid Ccell tumors noted in animal studies The lawsuits generally claim that manufacturers, including Novo Nordisk, failed to provide adequate warnings about drugs like Ozempic, promoted offlabel use for weight loss without proper risk disclosures, and did not update labels or prescriber communications quickly enough as reports of side effects and other injuries came in

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