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These have mostly been observed in rodents, which are known to have more C-cells than humansbut it also has been reported in humans with liraglutide
Common triggers of mast cell activation include: Food allergens (dairy, gluten, alcohol, fermented foods) Environmental toxins (heavy metals, chemicals and VOCs) Stress and trauma Chronic infections (Lyme, Epstein-Barr, Candida, SIBO) Mold and mycotoxin exposure When mast cells are constantly activated, histamine release becomes excessive, leading to chronic inflammation, tissue damage, and widespread symptoms that seem to come from nowhere
Gut protection reducing inflammation and supporting healing of ulcers or intestinal injury
Even then -- it is not a first step in any treatment not an "end all, be all"
Berna MJ, Seiz O, Nast JF et al
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