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It is not approved as a pharmaceutical or supplement
The foundational research here traces back to Loren Pickart, whose decades of work culminated in a widely cited 2018 review in the International Journal of Molecular Sciences documenting that GHK-Cu modulates the activity of thousands of human genes tied to tissue remodeling, antioxidant defense, and inflammatory regulation
Additionally, the synthesis of LDL receptors increases to allow increased cholesterol uptake for bile acid synthesis, and the overall effect is a reduction in plasma cholesterol
These failures may be traced to the use of inappropriate biomarkers as guides to treatment development
And another consideration: handling
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