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Substituting GIPRs C-terminal tail with that of GLP-1R significantly increased both the rate and extent of agonist-mediated endocytosis, suggesting a role for GIPRs C-terminal region in either its slower internalization or rapid recycling back to the plasma membrane
Interestingly, the cholesterol levels were similar among both groups, showing that theres likely an interaction with visceral fat (or inflammation) and atherosclerosis.[ref] Theres a trend among some health and wellness influencers to minimize the risk of high Lp(a) levels based on a specific study, such as this study showing that visceral fat influences atherosclerosis
Plain language summary Hundreds of millions of people around the world live with rare diseases, but most of these conditions still dont have effective treatments
Olivia de Rougemont is GP Lead at MedExpress, with over 14 years experience across the NHS and private sectors
Wang G, Gao S, Su N, Xu J, Fu D
