The American College of Gastroenterology's 2021 guideline on irritable bowel syndrome management issued a conditional recommendation against the use of probiotics for global IBS symptoms, citing very low overall quality of evidence.[8] IBS is not the same as GLP-1 constipation, but it overlaps in terms of dysmotility-driven symptoms, and the guideline tone signals appropriate caution about probiotic claims in this neighborhood
Their effects range across appetite, energy levels, the vascular system, inflammation, and sexual function
Longer-term cellular repair goals are harder to measure without lab work and clinician oversight
However, the need for daily adherence may be a drawback for people who struggle to stay on top of a daily regimen
If youre looking to take citrulline in supplement form, Peart recommends taking L-citrulline rather than citrulline malate