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PO phenytoin has ~90% bioavailability, so a 1:1 conversion is often used to convert between PO and IV administration
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An RCT in obese patients found that GLP-1 receptor activation by the agonist exenatide reduced brain responses on functional MRI to food cues in appetite- and reward-related brain areas including the insula and amygdala, correlating with reductions in food intake [18]
Haldys K, et al
SMJ contributed to conclusion and reviewed/edited manuscript
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