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Expert recommendations for pregnancy and breastfeeding Discontinuing GLP-1 medications before pregnancy If you are planning to become pregnant, discontinue GLP-1 medications at least two months before conception

See an eye specialist (ophthalmologist) for the eye symptoms themselves, and keep your GP or prescriber informed about the medication

How can the benefits of these medications be maximized

The short-acting GLP-1 receptor agonists primarily lower postprandial blood glucose levels through inhibition of gastric emptying, whereas the long-acting compounds have a stronger effect on fasting glucose levels, which is mediated predominantly through their insulinotropic and glucagonostatic actions

Tigylglycine is an N -acylglycine formed from glycine with an amine hydrogen substituted by a 2-methylbut-2-enoyl (tiglyl) group