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Notably, gene-expression studies have associated GHK-Cu with the modulation of thousands of genes tied to tissue remodeling and the inflammatory response, which is why it is studied as a foundational signal peptide in repair models

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Ann N Y Acad Sci 2004;1033:30-41

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GH-mediated changes are slow, meaningfully slower than testosterone or GLP-1 results, because they work through downstream protein synthesis and tissue remodeling