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C1-27 , cisplatin (1 M, dissolved in 0.9% NaCl), PD98059 (10 M), LY294002 (10 M), SP600125 (1 M) or desferoxamine mesylate (10 M) were added alone or in combination and colonies were allowed to grow for 710 days

To find out why, researchers tested the liver cells to see what had changed in the depressed mice

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