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Hg exposure levels even at low concentrations (1.0 and 1.5 mg/L) can be toxic for plants that lead to disruption of cellular function, plant growth, and development [30]
Dosage adjustment of thyroid hormone replacements is still an art since inappropriate dosing can result in symptoms of overtreatment or undertreatment with further complications including cardiovascular problems, loss of bone density, and neurological disturbances
Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization
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