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Furmonertinib (AST2818) versus gefitinib as first-line therapy for Chinese patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer (FURLONG): a multicentre, double-blind, randomised phase 3 study

Mechanistic Insights

Interactions between GSH and OH resulted in the abstraction of the thiol H-atom, leading to the formation of a water molecule and a glutathione radical (GS), located on the cysteine

Some inject once at bedtime, and some break doses morning and evening

Although direct mechanisms by which microglia interact with mature OLs to regulate their responses are not clear, a study in zebrafish showed that microglia engulf myelin sheaths to regulate sheath number in developmental myelination 174