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Some researchers believe those who have a goal for more significant weight loss may be relatively better candidates for prescription weight loss drugs compared to those with more modest weight loss goals

However, many patients find that their eating habits and food preferences have shifted permanentlyyou may continue choosing smaller portions and less sugary foods even after the medication's hunger-suppressing effect ends

This week in the Lancet Gastroenterology and Hepatology, the researchers reported that the meaningful microscopic improvements in liver tissue they saw at 48 weeks on the biopsy samples were associated with clinically meaningful improvements in certain blood tests that were already evident after only 12 weeks

( B ) Box-and-whisker plots of fasting plasma concentrations of BB from subjects ( n = 9) before versus after 1 week of oral broad-spectrum antibiotics to suppress gut microbiota

Lancet Diabetes Endocrinol 8(4):313324