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Too much NNMT can lower NAD+ levels (low NAD+ levels may make it harder to burn fat efficiently or maintain metabolic health as you age)

Presented for research literature review only Cooke A et al

Properly stored (refrigerated, protected from light), GHK-Cu reconstituted with bacteriostatic water remains stable approximately 30 days

None of this is surprising, since oxidative stress is closely linked with other forms of aging as well