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Electrospray of a coordination complex is unreliable in a way that catches people out: the complex can dissociate in the source, so the ion you observe may well be the free tripeptide rather than the copper adduct
The rectangular boxes indicate substrates, and the blue or yellow ovals give the names of the enzymes catalyzing the reactions
Novo Nordisk's semaglutide (Wegovy) achieved 14.9% weight loss in its landmark STEP 1 trial over 68 weeks a single GLP-1 agonist that first demonstrated the class's potential in obesity
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