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19 Sarah Lewis is a pharmacist and a medical writer with over 25 years of experience in various areas of pharmacy practice
This scoping review was carried out in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews) guidelines
10.1016/j.coph.2007.04.004 Curr
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Seek immediate medical attention (call 911 for severe symptoms) if you experience: Chest pain, pressure, or discomfort, particularly if new or worsening Severe shortness of breath or difficulty breathing at rest Rapid or irregular heartbeat accompanied by dizziness or lightheadedness Swelling in the legs, ankles, or abdomen that develops suddenly or worsens Unexplained fatigue or exercise intolerance that significantly limits daily activities These symptoms may indicate cardiovascular complications unrelated to tirzepatide itself but requiring urgent evaluation, especially in patients with diabetes and obesity who have elevated baseline cardiovascular risk
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