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In the outcome of changes in the ALT levels, moderate credibility of ICEMAN result shows that L-carnitine supplementation has no difference in changes in younger ones (MD: 0.4, 95%CI: 1.32 to 2.12) but has significant changes (reduced) in adults (MD: 31.7, 95%CI: 47.61 to 15.79)

L-Carnitine helps support this delicate balance, particularly during times of calorie restriction

The SURPASS-1 trial investigated the efficacy and safety of the three doses of 5, 10, or 15 mg tirzepatide in drug-nave patients with T2D who were not sufficiently controlled with a lifestyle intervention with diet and exercise versus placebo (70)